Proposal of a Convolutional Neural Network Based Prediction Model for Prostate Cancer from MRI
Glad LUFIMPU MAMPUYA *
Faculty of Science and Technology, Department of Mathematics, Statistics and Computer Science, National Pedagogical University (UPN), Democratic Republic of the Congo.
Pierre KAFUNDA KATALAY
Faculty of Science and Technology, Department of Mathematics, Statistics and Computer Science, University of Kinshasa (UPN), Democratic Republic of the Congo.
Richard KITONDUA LUBANZADIO
Faculty of Science and Technology, Department of Mathematics, Statistics and Computer Science, National Pedagogical University (UPN), Democratic Republic of the Congo.
Cédric KABEYA TSHISEBA
Faculty of Science and Technology, Department of Mathematics, Statistics and Computer Science, National Pedagogical University (UPN), Democratic Republic of the Congo.
Francis MAYALA LEMBA
Faculty of Science and Technology, Department of Mathematics, Statistics and Computer Science, National Pedagogical University (UPN), Democratic Republic of the Congo.
Hervé TSHIMUNYI KAYEMBE
Faculty of Science and Technology, Department of Mathematics, Statistics and Computer Science, National Pedagogical University (UPN), Democratic Republic of the Congo.
Christ TSUNGU MUJIMBU
Faculty of Science and Technology, Department of Mathematics, Statistics and Computer Science, National Pedagogical University (UPN), Democratic Republic of the Congo.
Camile LIKOTELO BINENE
Faculty of Science and Technology, Department of Mathematics, Statistics and Computer Science, National Pedagogical University (UPN), Democratic Republic of the Congo.
Christophe FUMUMUIKI
Faculty of Science and Technology, Department of Mathematics, Statistics and Computer Science, National Pedagogical University (UPN), Democratic Republic of the Congo.
Caleb BATATA
Exact Sciences Section, Department of Mathematics and Computer Science, ISP-GOMBE, Democratic Republic of the Congo.
Sylvain-Mozart NGANDU KANUMAYI
Faculty of Science and Technology, Department of Mathematics, Statistics and Computer Science, University of Kinshasa (UPN), Democratic Republic of the Congo.
*Author to whom correspondence should be addressed.
Abstract
The use of convolutional neural networks (CNNs) in the medical field has revolutionized diagnosis, particularly for prostate cancer, one of the most common cancers in men. Early diagnosis is crucial to improve treatment outcomes. MRI is a key imaging modality, providing detailed information about prostate tissue, but its interpretation can be subject to subjectivity depending on the expertise of radiologists. The application of CNNs for prostate MRI analysis represents a significant advance in diagnosis. This model can thus serve as a decision support tool for radiologists, improving diagnostic accuracy and, potentially, clinical outcomes.
The proposed model demonstrated high predictive power for prostate cancer, with high performance in terms of accuracy, sensitivity, and specificity. ROC curves illustrated good discrimination between positive and negative cases. This approach demonstrates the potential of artificial intelligence in complex medical diagnosis, and future studies could explore the integration of this model into clinical systems for use in real-world settings.
The proposed model for prostate cancer prediction demonstrated excellent performance, particularly in terms of accuracy, sensitivity, and specificity. The model's effectiveness was evaluated using Receiver Operating Characteristic (ROC) curves, a fundamental tool for assessing the performance of binary classifiers. These curves plot the true positive rate (sensitivity) against the false positive rate, allowing the model's ability to correctly distinguish between positive cases (patients with cancer) and negative cases (healthy patients) to be evaluated. The closer the ROC curve is to the top-left corner of the plot, the better the model's performance. In this study, the resulting ROC curve exhibited outstanding discrimination, confirming the robustness of the proposed predictive system. These findings highlight the potential of artificial intelligence, particularly neural networks, in the field of computer-aided medical diagnosis. Future research could focus on the practical integration of this model into clinical systems to enhance early detection of prostate cancer in real-world settings.
Keywords: Artificial intelligence, convolutional neural networks, MRI, prostate cancer, deep learning